Devita, Hellman, and Rosenberg's Cancer

LWBK1006-Index LWW-Govindan-Review December 19, 2011 19:14

616 Index

Pancreatic intraepithelial neoplasms

(PanIN), 243, 247–248

Pancytopenia, 447

p53 and DNA damage, 98, 102

Panhypopituitarism, 223

PanIN.SeePancreatic

intraepithelial neoplasms

(PanIN)

Panitumumab, 273, 277

Papillary mesothelioma, surgical

resection in, 490, 494

Papillary serous adenocarcinoma,

477

Papillary thyroid carcinoma, 356,

363

dedifferentiated, 351, 359

poor prognostic features of, 351,

359

RET/PTC rearrangement in, 351,

359

and thyroid hormone

replacement, 349, 358

total thyroidectomy for, 349, 358

Papillomatous lesions, 160

Parameningeal disease, 409

Paraneoplastic neurologic

syndromes, 53

Paraneoplastic pemphigus, 224

Paraneoplastic syndromes, 217,

222, 223–224, 517–524

Parathyroid carcinoma, 353, 361

genetic defects with, 353, 361

management of, 353, 360

Parents with cancer, guidelines for,

561, 567

Parosteal osteosarcoma, 373

treatment, 368, 373

PARP.SeePoly (ADP-ribose)

polymerase (PARP)

PARP1, 331, 341

Partial response (PR), 96, 101, 452,

456

Parvovirus B19 infection, 544, 549

Patient-reported outcomes, in

oncology research, 116, 120

PCI.SeeProphylactic cranial

irradiation (PCI)

PCNSL.SeePrimary CNS

lymphoma (PCNSL)

PCR.SeePolymerase chain reaction

(PCR)

PC-SPES, for prostate cancer

treatment, 591, 595

11p, deletion of, 478

Pelvic floor exercises, 576, 579

Pelvic lymphadenectomy, 327

Pelvic percutaneous biopsies and

ovarian cancer, 162

Pemetrexed, 24, 32, 124, 129

for NSCLC treatment, 206, 211

Penetrance, defined, 150, 155

Penile cancer, 295

and HPV, 39, 51

P450 enzymes 1A1, 1A2 and

cigarette smoke, 33, 43

Peptic ulcers treatment, radiation

in, 59, 64

Peptidome, 3, 10

Percutaneous biliary drainage, 163,

172

Percutaneous cholecystostomy, 163,

172–173

Percutaneous gastrostomy tubes,

162, 171

Percutaneous nephrostomy, 163,

171

Performance status (PS), 206

Pericardial cysts, occurrence of, 222

Pericytes, 21, 29

Peripheral blood mobilized stem

cell allografts, 528, 534

Peripheral nerve blocks, for cancer

pain, 565, 570

Peripheral primitive

neuroectodermal tumor

(pPNET), 395, 405

Peripheral T cell lymphomas

(PTCL), 435

Peritoneal carcinomatosis, 477,

487–495

appendiceal cancer and, 487

BRCA1 mutation and, 480

extra-abdominal organs and, 487

free-floating tumor cells, 487, 492

intra-abdominal viscera and, 487

isolated, 487, 492

magnetic resonance imaging for,

488, 492

ovarian cancer and, 487

peritoneal lining and, 487

pressure-burst phenomenon, 487,

492

surgical intervention in, 489, 493

tumors in, 487, 492

Peritoneal mesothelioma, 484, 485

epithelial type of, 489, 494

malignant, 490, 494

risk factor for, 489, 494

surgical cytoreduction and

intraperitoneal

chemotherapy, 490, 494

Peritoneal shunts, 495

Peritoneovenous shunt, 512, 515

PET.SeePositron emission

tomography (PET)

Peutz-Jeghers syndrome, 154, 160,

332, 341

Phantom-hCG, 322, 329–330

Phenothiazines, 552

Phenotypic markers, analysis of,

72, 76

Phenytoin, 526, 532

Pheochromocytoma, 356, 362–363

Philadelphia chromosome, 448

in ALL, 452, 457

in AML, 452, 457

in CML, 452, 457

Phosphatidylinositol 3 kinase

signaling, 15

Phosphoinositide 3 (PI3), 25

Phospholipase C proteins, 7, 16

Phospholipid lipid growth factor

(PLGF), 20

Photons, skin-sparing effect of, 93

Physically inactive

colon cancer risk and, 62, 68

postmenopausal breast cancer

and, 62, 68

Physical therapy, 577

Physician-assisted suicide, 586

PI3.SeePhosphoinositide 3 (PI3)

PI3-kinase/AKT pathway, mTOR

in, 19

PI3-kinase pathway and mTOR, 32

Pilocarpine, 577

xerostomia and, 554, 558

Pilocytic astrocytoma, 384, 389

PIN.SeeProstate intraepithelial

neoplasia (PIN)

p16INK4a, 2, 8

expression of, 6, 14

Placental alkaline phosphatase

(PLAP), 297, 301

Plasma cell leukemia

diagnostic criterion for, 473

incidence of, 467

Plasma cell neoplasms, 463–473

Plasmacytoma, solitary bone,

472–473

Platelet-derived growth factor

receptor, 6

Platinum analogs, 573, 577

Platinum-based chemotherapy

Merkel cell carcinoma and, 378,

381

for ovarian cancer, 308, 309, 312,

314

Pleural mesothelioma and asbestos,

57, 63

PLGF.SeePhospholipid lipid

growth factor (PLGF)

Plicamycin, for reduction in

calcium level, 508

Plummer-Vinson syndrome, 142,

145

PLX4032 drug andBRAFgene, 24,

32