Chapter 6 Percutaneous Coronary InterventionABCFig. 6.2 Relative risk of outcomes with
early invasive versus conservative therapy
in UA/NSTEMI. (a) Relative risk of all-
cause mortality for early invasive therapy
compared with conservative therapy at a
mean follow-up of 2 years. (b) Relative
risk of recurrent nonfatal MI for early
invasive therapy compared with
conservative therapy at a mean follow-up
of 2 years. (c) Relative risk of recurrent
UA resulting in rehospitalization for early
invasive therapy compared with
conservative therapy at a mean follow-up
of 13 months. CI indicates confi dence
interval; FRISC-II, FRagmin and fast
Revascularization during InStability in
Coronary artery disease; ICTUS, Invasive
versus Conservative Treatment in Unstable
coronary Syndromes; ISAR-COOL,
Intracoronary Stenting with Antithrombotic
Regimen COOLing-off study; RITA-3,
Third Randomized Intervention Treatment
of Angina trial; RR, relative risk; TIMI-18,
Thrombolysis In Myocardial Infarction-18;
TRUCS, Treatment of Refractory Unstable
angina in geographically isolated areas
without Cardiac Surgery; and VINO, Value
of fi rst day angiography/angioplasty In
evolving Non-ST segment elevation
myocardial infarction: Open multicenter
randomized trial. Reprinted from the
Journal of the American College of
Cardiology, vol. 48, Bavry AA, Kumbhani
DJ, Rassi AN, Bhatt DL, Askari AT. Benefi t
of early invasive therapy in acute coronary
syndromes: a meta-analysis of
contemporary randomized clinical trials,
pp. 1319–1325, Copyright 2006 by
American College of Cardiology
Foundation.