The AHA Guidelines and Scientifi c Statements Handbook
Classic claudication symptoms:
Muscle fatigue, cramping, or pain that reproducibly begins during exercise and
that promptly resolves with rest
Chart document the history of walking impairment (pain-free and total walking
distance) and specific lifestyle limitations
Document pulse examination
ABI less than or equal to 0.90
Confirmed PAD diagnosis
Go to Figure 9.5, Treatment of Claudication
Risk factor normalization:
Immediate smoking cessation
Treat hypertension: JNC-7 guidelines
Treat lipids: NCEP ATP III guidelines
Treat diabetes mellitus: HbAlc less than 7%*
Pharmacological risk reduction:
Antiplatelet therapy
(ACE inhibition;† Class IIa)
ABI
Exercise ABI
(TBI, segmental
pressure, or duplex
ultrasound
examination)
No PAD or
consider arterial
entrapment
syndromes
ABI greater
than 0.90
Abnormal
results
Normal
results
Fig. 9.4 Diagnosis of claudication and systemic risk treatment.
- It is not yet proven that treatment of diabetes mellitus will signifi cantly reduce peripheral arterial disease (PAD)-specifi c (limb ischemic) endpoints. Primary
treatment of diabetes mellitus should be continued according to established guidelines.
† The benefi t of angiotensin-converting enzyme (ACE)-inhibition in individuals without claudication has not been specifi cally documented in prospective clinical
trials, but has been extrapolated from other “at risk” populations.
ABI, ankle-brachial index; HgbA1c, hemoglobin A; JNC-7, Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment
of High Blood Pressure; LOE, level of evidence; NCEP ATP-III, National Cholesterol Education Program Adult Treatment Panel III.
Exercise and lower extremity pad rehabilitation
See Table 9.7.
Class I
1 A program of supervised exercise training is rec-
ommended as an initial treatment modality for
patients with intermittent claudication. (Level of
Evidence: A)
2 Supervised exercise training should be performed
for a minimum of 30 to 45 minutes, in sessions
performed at least three times per week for a
minimum of 12 weeks. (Level of Evidence: A)
Class IIb
The usefulness of unsupervised exercise programs is
not well established as an effective initial treatment
modality for patients with intermittent claudication.
(Level of Evidence: B)