Hypertension
Clive Rosendorff
11
Introduction
Benefi ts of lowering BP
BP control rates
Blood pressure measurement in the clinic or the offi ce
Patient evaluation
Laboratory tests and other diagnostic procedures
Tr e a t m e n t
Lifestyle modifi cations
Pharmacologic treatment
Uncomplicated hypertension
Special considerations
CAD and stable angina
Unstable angina, non-ST-elevation myocardial
infarction (NSTEMI), and ST-elevation myocardial
infarction (STEMI)
Heart failure
Diabetes
Treatment
Chronic kidney disease (CKD)
Defi nition of CKD
Hypertension as a risk factor for CKD progression
Hypertension as a consequence of CKD
Lifestyle modifi cations
Pharmacologic therapy
Endocrine disease and pregnancy
African-Americans
Future directions
Acknowledgements
Introduction
This chapter on hypertension is a summary of, and
contains verbatim extracts from, the following
guideline statements: Seventh Report of the Joint
National Committee on Prevention, Detection,
Evaluation, and Treatment of High Blood Pressure
- JNC 7 (2003) [1,2]; Recommendations for Blood
Pressure Measurement in Humans and Experimen-
tal Animals. Part 1: Blood Pressure Measurement in
Humans, a Statement from the Subcommittee of
Professional and Public Education of the American
Heart Association Council on High Blood Pressure
Research (2005) [3]; Treatment of Hypertension in
the Prevention and Management of Ischemic Heart
Disease; a Scientifi c Statement from the American
Heart Association Council for High Blood Pressure
Research and the Councils on Clinical Cardiology
and Epidemiology and Prevention (2007) [4];
Dietary Approaches to Prevent and Treat Hyperten-
sion. A Scientifi c Statement from the American
Heart Association (2006) [5]; the American Diabe-
tes Association Guidelines for the Treatment of
Hypertension in Adults with Diabetes (2003) [6];
the K/DOQI Clinical Practice Guidelines on Hyper-
tension and Antihypertensive Agents in Chronic
Kidney Disease (2004) [7]; and the Consensus State-
ment of the Hypertension in African Americans
Working Group of the International Society on
Hypertension in Blacks on the Management of
Hypertension in African Americans (2003) [8].
Comparisons will also be made with the guidelines
developed in 2007 by the European Society of
Hypertension and the European Society of Cardiol-
ogy [9]. The recommendations for the pharmaco-
logic management of hypertension described in this
chapter do not include comprehensive information
about antihypertensive drugs; clinicians are strongly
advised to read the FDA-approved labeling of each
drug before prescribing. In particular each drug has
a list of specifi c contraindications which should be
carefully reviewed.
The AHA Guidelines and Scientific Statements Handbook
Edited by Valentin Fuster © 2009 American Heart Association
ISBN: 978-1-405-18463-2