Effects on Development 653References
Araki W, Wurtman RJ (1997) Control of membrane phosphatidylcholine biosynthesis by
diacylglycerol levels in neuronal cells undergoing neurite outgrowth. Proc Natl Acad Sci
USA 94:11946–11950
Asch RH, Smith CG (1986) Effects of∆^9 -THC, the principal psychoactive component of
marihuana, during pregnancy in the rhesus monkey. J Reprod Med 31:1071–1081
Berrendero F, García-Gil L, Hernández ML, Romero J, Cebeira R, de Miguel R, Ramos JA,
Fernández-Ruiz JJ (1998) Localization of mRNA expression and activation of signal
transduction mechanisms for cannabinoid receptors in rat brain during fetal develop-
ment. Development 125:3179–3188
Berrendero F, Sepe N, Ramos JA, Di Marzo V, Fernández-Ruiz JJ (1999) Analysis of cannabi-
noid receptor binding and mRNA expression and endogenous cannabinoid contents
in the developing rat brain during late gestation and early postnatal period. Synapse
33:181–191
Biegon A, Kerman IA (2001) Autoradiographic study of pre- and postnatal distribution of
cannabinoids receptors in human brain. Neuroimage 14:1463–1468
Bonnin A, de Miguel R, Castro JG, Ramos JA, Fernández-Ruiz JJ (1996) Effects of perinatal
exposure to∆^9 -tetrahydrocannabinol on the fetal and early postnatal development of
tyrosine hydroxylase containing neurons in rat brain. J Mol Neurosci 7:291–308
Burden-Galley SM, Pendergast M, Lemmon V (1997) The role of cell adhesion molecule
L1 in axonal extension, growth cone motility, and signal transduction. Cell Tissue Res
290:415–422
Corchero J, Garcia-Gil L, Manzanares J, Fernández-Ruiz JJ, Fuentes JA, Ramos JA (1998)
Perinatal∆^9 -tetrahydrocannabinol exposure reduces proenkephalin gene expression in
the caudate-putamen of adult female rats. Life Sci 63:843–850
Dalterio SL (1980) Perinatal or adult exposure to cannabinoids alter male reproductive
functions in mice. Pharmacol Biochem Behav 12:143–153
Dalterio SL (1986) Cannabinoid exposure: effects on development. Neurobehav Toxicol
Teratol 8:345–352
Dalterio SL, Barker A (1979) Perinatal exposure to cannabinoids alter male reproductive
functions in mice. Science 205:1420–1422
Del Olmo E, Pazos A (2001) Aminergic receptors during the development of the human
brain: the contribution of in vitro imaging techniques. J Chem Neuroanat 22:101–114
Di Marzo V (1998) Endocannabinoids and others fatty acid derivatives with cannabimimet-
ics properties: biochemistry and possible physiopathological relevance. Biochim Bio-
phys Acta 1392:153–175
Fernández-Ruiz JJ, Rodriguez de Fonseca F, Navarro M, Ramos JA (1992) Maternal cannabi-
noid exposure and brain development: changes in the ontogeny of dopaminergic neu-
rons. In: Bartke A, Murphy LL (eds) Neurobiology and neurophysiology of cannabi-
noids, biochemistry and physiology of substance abuse, vol IV. CRC Press, Boca Raton,
pp 119–164
Fernández-Ruiz JJ, Bonnin A, Cebeira M, Ramos JA (1994) Ontogenic and adult changes
in the activity of hypothalamic and extrahypothalamic dopaminergic neurons after
perinatal cannabinoid exposure. In: Palomo T, Archer T (eds) Strategies for studying
brain disorders, vol I. Farrand Press, London, pp 357–390
Fernández-Ruiz JJ, Romero J, García-Gil L, Garcia-Palomero E, Ramos JA (1996) Dopamin-
ergic neurons as neurochemical substrates of neurobehavioral effects of marihuana:
developmental and adult studies. In: Beninger RJ, Archer T, Palomo T (eds) Dopamine
disease states. CYM Press, Madrid, pp 359–387
Fernández-Ruiz JJ, Muñoz RM, Romero J, Villanúa MA, Makriyannis A, Ramos JA (1997)
Time-course of the effects of different cannabimimetics on prolactin and gonadotropin
secretion: evidence for the presence of CB1 receptors in hypothalamic structures and
their involvement in the effects of cannabimimetics. Biochem Pharmacol 53:1919–1927