133a patient-acceptable status. A change of 3 or more points is considered a relevant
absolute change [ 63 ]. The PsAID questionnaires are available online free of charge
with their available translations.
Dermatological Life Quality Index
The Dermatological Life Quality Index (DLQI) was not developed for PsA: It is a
psoriasis questionnaire. The DLQI is a 10-item questionnaire assessing the effect of
psoriasis on daily activities and level of disability over the previous 7 days [ 64 ]. The
DLQI questions are grouped into six subcategories: symptoms and feelings, daily
activities, leisure, work/school, personal relationships, and treatment. DLQI is a
validated questionnaire with scores ranging from 0 to 30, with higher scores indicat-
ing more impairment. Although the DLQI is not per se a function tool, it has been
used in some studies as a measure of dermatological-related functional limitations
[ 65 ]. The MCID for the DLQI has not been established for PsA , but in psoriasis
patients it has been estimated as a 5-point improvement [ 66 ].
Widely Used, Nonspecifi c PROs in PsA
We will review here some of the generic PROs most frequently used in the context
of PsA, in particular in PsA clinical trials [ 48 ].
Single Questions Used in PsA
Single questions are usually in the format of VAS or NRS. Both of these are reported
with a fi gure from 0 to 10, or 0 to 100, where 0 is usually perfect status, and 10 or
100 usually the worst status [ 67 ].
Patient Global Assessment
PGA is one of the most widely used PRO s in PsA [ 48 , 68 ] and is usually assessed by the
following question: “Considering all the ways psoriatic arthritis has affected you during
the last week, circle the number that best describes how you have been doing” [ 67 ].
PGA is an overall measure of the patient status, and is included in several com-
posite measures of disease activity such as the Psoriatic Arthritis Disease Activity
Score (PASDAS) or the defi nition of Minimal Disease Activity [ 69 – 71 ].
Recently GRAPPA has also suggested using other “patient global” questions
specifi c to joints and skin. The joint and skin patient assessments, respectively, ask
5 PROMs for Spondyloarthritis