74
for completion at each visit as part of the infrastructure of care. Indeed, MDHAQ
saves time for the doctor by providing a 10–15 s overview of medical history data
that would otherwise require about 10–15 min of conversation, including the
self- report joint count, fatigue VAS, improvement scale, symptom checklist, and
recent medical history.
RAPID3 is scored in 5 s, as noted previously, compared to about 40 s for a HAQ,
90–95 s for a formal joint count, 104 s for a CDAI, and 116 s for a DAS28 [ 71 ]
(Fig. 3.6 ). RAPID3 levels for high, moderate, low disease severity and remission
can be used effectively for “treat-to-target” in RA. Unlike a formal joint count,
MDHAQ/RAPID3 does not require the same examiner at each assessment, as a
Fig. 3.7 Spearman correlations of RAPID3 (routine assessment of patient index data 3) scores with
( a , c ) the Disease Activity Score (DAS28) and (B, D) Clinical Disease Activity Index (CDAI) in ( a ,
b ) the rheumatoid arthritis prevention of structural damage (RAPID1) clinical trial of certolizumab
pegol in 982 patients at 52 weeks and ( c , d ) in 285 patients with RA seen in usual clinical care
T. Pincus et al.