Clinical_Rounds_in_Endocrinology_Volume_II_-_Pediatric_Endocrinology

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fertile eunuch syndrome, minimal androgen insensitivity syndrome (MAIS),

and juvenile hypothyroidism. In addition, acquired hypogonadotropic

hypogonadism may also result in undervirilization with normal-sized but

soft testes (e.g., prolactinoma, nonfunctioning pituitary macroadenoma)

(Figs. 7.21 and 7.22).

ab

Fig 7.21 (a) A 16-year-old boy had testicular volume of 15 ml with poor virilization. (b) CEMRI
sella showing giant pituitary macroadenoma. Serum prolactin was 4,794 ng/ml, confirming the
diagnosis of prolactinoma

7 Delayed Puberty