Clinical_Rounds_in_Endocrinology_Volume_II_-_Pediatric_Endocrinology

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Fig. 2.5 ( a ) A 21-year-old boy with panhypopituitarism and septo-optic dysplasia. ( b ) Fundus
examination showing temporal pallor of left optic disc. ( c ) Electroretinogram depicting absence of
a and b wave in the left eye. ( d ) Visual evoked responses revealed absence of waveforms in the left
eye. ( e ) CEMRI sella demonstrating classical tetrad (ectopic posterior pituitary bright spot, red
arrow ) of pituitary transcription factor defect. ( f ) Coronal MR image depicting left optic nerve
hypoplasia as compared to right optic nerve ( red arrow )

a

b

2 Disorders of Growth and Development: Diagnosis and Treatment