b2815 Tissue Engineering and Nanotheranostics “9.61x6.69”128 Tissue Engineering and Nanotheranostics
research techniques have been employed in the diagnosis of cancer,
such as, positron emission tomography (PET), computed tomog-
raphy (CT), MRI and optical microscopy in the bioimaging fields.
Among them, MRI is a more advanced and promising non-invasive
diagnostic technique owing to its sensitivity, selectivity, undisrup-
tive, multiplanar capabilities, and tissue characterization potential
and particularly, MRI does not contain ionizing radiation (high-
energy radiation that can potentially cause damage to DNA, like
the X-rays used for CT scans). It is the innovative technique which
is employed mutually in research and clinical applications to map
the tissues and organs in the body, for example, in injuries and
Fig. 19. “Tug-of-war” behavior in Au 2 –Au 1 –Fe 3 O 4 dumbbell nanoparticles.
(a) Graphical presentation of the Au 2 nanomaterial overgrowth on Au 1 NP and
Au 1 NP separation from the Fe 3 O 4 NP, shaping a new dumbbell-like structure of Au 1 –
Au 2 and the scratched Fe 3 O 4 NPs. Also, fusion of the Au component of two Au–
Fe 3 O 4 NPs leads to the synthesis of Fe 3 O 4 –Au–Fe 3 O 4 Janus nanohybrids.
(b) TEM pictures of the different growth stages of magnetic–plasmonic nanostruc-
tures. (c) Various growth levels of Fe 3 O 4 –Ag–Pt corresponding with TEM images.
Reprinted with permission from Refs. 94–96.