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“9.61x6.69” b2815 Tissue Engineering and Nanotheranostics

Chapter 7

Delivering Nanoparticles

to Cancer Cells

Ronald L. Huston

Department of Mechanical and Materials Engineering

College of Engineering and Applied Sciences

University of Cincinnati

Cincinnati, OH 45221-0072, USA

Abstract: In this chapter, we present a new nanoparticle methodo­

logy for treating cancerous tumors. The methodology is based

upon a characteristic of cancer cells: that is, cells with an excess of

centrioles. Centrioles are small cylindrical organelles lying adjacent

to the nucleus. They create the electromagnetic field in a cell. But

with an excess of centrioles, the electromagnetic field is enhanced.

This enhancement then provides a biomarker for magnetically

charged toxic nanoparticles. The chapter provides a basis for these

assertions.

Keywords: Cancer, centrioles, microtubules.

1. Introduction

Many people (myself included) believe that the use of nanoparticles

to image and destroy cancerous tumors is the greatest envisioned

application in all of nanotechnology.1,2