Tissue Engineering And Nanotheranostics

(Steven Felgate) #1
b2815 Tissue Engineering and Nanotheranostics “9.61x6.69”

212 Tissue Engineering and Nanotheranostics


Fig. 5. A sketch of an a/b tubulin dimer.

a and b tubulin proteins. The a and b tubulin have positive and


negative charges and taken as a pair (a “dimer”), they may be viewed


electrically as a simple battery — as used in a flashlight.


If the a/b dimers are modeled as a short cylinder, the diameter is


approximately 5 nm and the length 10 nm. Thus a typical microtu­


bule filament contains approximately 40 a/b dimers.


The microtubule cylinder has 13 parallel filaments. These fila­


ments are believed to be able to move longitudinally, independent of


one another. Figures 5–7 provide sketches of an a/b dimer, a fila­


ment, and a microtubule cylinder.

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