b2815 Tissue Engineering and Nanotheranostics “9.61x6.69”216 Tissue Engineering and Nanotheranostics
Once a second pair of centrioles is formed, the younger pair will
break away from the original pair and move to the opposite side of the
nucleus — as noted earlier. But during this movement the younger
centriole pair becomes more mature, increasing in size so that by the
time it is on the opposite side of the nucleus it is of equivalent vitality
as the older centriole pair is left behind. Cell separation can then
occur by the opposing centriole pairs, extending their microtubules
about the nucleus and connecting to the kinetochores at the mid
plane of the nucleus. Once these connections occur the nucleus is
pulled apart with each half taking approximately half of the cytoplasm.
Thus two cells are formed. See Fig. 10.
Fig. 10. Cell duplication and separation.