Table 1 Proteomics in personalized medicine—selected references
Allergy Cevera J, Locascio L (2012) New and improved proteomics tech-
nologies forunderstanding complex biological systems: Addressing
a grand challenge in the life sciences. Proteomics 12:2773–2783
Chuang JG, Su SN, Chiang BL, Lee HJ, Chow LP (2010) Proteome
mining for novel IgE-binding proteinsfrom the German cockroach
(Blattella germanica) and allergen profiling of patients. Proteomics
10:3854–3867
Halim A, Carlsson MC, Madsen CB, Brand S, Møller SR, Olsen
CE, Vakhrushev SY, Brimnes J, Wurtzen AP, Ipsen H, Petersen
BL, Wandall HH (2015) Glycoproteomic analysis of seven major
allergenic proteins reveals novel post-translational modifications.
Mol Cell Proteomics 14:191–204
Holm T, Rutishauser D, Kai-Larse Y, Lyutvinskiy Y, Stenius F,
Zubarev RA, Agerberth B, Alm J, Scheynius A (2013) Protein
biomarkers in vernix with potential to predict the development of
atopic eczema in early childhood. European Journal of Allergy and
Clinical Immunology 69:104–112
Hood LE, Omenn GS, Moritz RL, Aebersold R, Yamamoto KR,
Amos M, Hunter-Bluggel M, Spertini F, Lutter P, Wassenberg J,
Audran R, Corthesy B, Mullner S, Blum S, Wattenberg A,
Mercenier A, Affolter M, Kussmann M (2011) Toward Protein
Biomarkers for Allergy: CD4þ T Cell Proteomics in Allergic and
Nonallergic Subjects Sampled in and out of Pollen Season. J
Proteome Res 10:1558–1570
Huang LC, Wu X, Chen JY (2013) Predicting adverse drug reac-
tion profiles by integrating protein interaction networks with drug
structures. Proteomics13:313–324
Sauer S, Luge T (2014) Nutriproteomics – facts, concepts and
perspectives. Proteomics doi:10.1002/pmic.201400383
Cancer Breast Tang Y, Mackey J, Lai R, Ghosh S, Santos C, Graham K,
Damaraju S, Pasdar M, Li L (2013) Quantitative proteomic anal-
ysis of HER2 normal and overexpressing MCF-7 breast cancer
cells revealed proteomic changes accompanied with HER2 gene
amplification. J Proteomics 91:200–209
Wulfkuhle JD et al. (2008) Multiplexed Cell Signaling Analysis of
Human Breast Cancer Applications for Personalized Therapy. J
Proteome Res 7:1508–1517
Colorectal Han CL et al. (2011) An Informatics-assisted Label-free Approach
for Personalized Tissue Membrane Proteomics: Case Study on
Colorectal Cancer. Molecular & Cellular Proteomics 10:1–15
Pierobon M, Silvestri A, Spira A, Reeder A, Pin E, Banks S,
Parasido E, Edmiston K, Liotta L, Petricoin E (2014) Pilot Phase
I/II Personalized Therapy Trial for Metastatic Colorectal Cancer:
Evaluating the Feasibility of Protein Pathway Activation Mapping
for Stratifying Patients to Therapy with Imatinib and
Panitumumab. J Proteome Res 13:2846–2855
Lung Varga GV et al. (2007) Personalized Medicine and Proteomics:
Lessons from Non-Small Cell Lung Cancer. J Proteome Res
6:2925–2935
(continued)The Role of Proteomics in Personalized Medicine 195