Systems approach:
Shift away from current
symptom-based disease model
Describe phenotypes
Systemic insightsInfrastructure:
Access to technology
Biobanks
Human resources
CohortsSharing mechanisms
Legal and ethical frameworks
Public-private partnership
Systemic data collectionHarmonisation:
Sample collection
Processing
Data handling
TerminologyFig. 2Key enabling factors
EducationStakeholder participationMultidisciplinarityInfrastructureRevised classification of diseaseRegulatory frameworksReimbursement modelsPersonalised Ethical, legal and social issues
medicine issuesFig. 1Key issues affecting the development and implementation of personalized medicine
Personalized Medicine: The Path to New Medicine 17