Other than pathogen detection the MF PoC devices include health care devices
for monitoring human health from analyzing different molecules from human
blood. Blood chemistry analysis is perhaps the most successful application of
these kinds of devices and the examples include i-STAT, Bioanalyzer 2100 from
agilent Technologies, epoc from Epocal etc. [ 73 , 80 ]. These devices provide
information about various ions like Na+,K+,Cl, blood pH, nitrogen content and
oxygen analysis in very short time duration [ 81 ].
3.2 Immunodiagnostics
Immunoassays are probably the most important protein analysis technique. These
are based on detection of either antigen or cytokines. Antibody-antigen based
detection is utilized for the detection of various diseases like hepatitis and autoim-
mune disorders whereas cytokines based assays are utilized for the studies of
CEInlet Microchannels 200 μmITOLB film deposition of QDImmobilization of DNA
OutletRE (Ag/AgCl wire)EIS
measurement3.0 cm
1.0 cm1.5 cmPDMS slabWEFig. 8.9 Different steps showing the fabrication of MF biochip for electrochemical detection of
DNA hybridization.WEworking electrode,CEcounter electrode,REreference electrode [ 74 ]
212 S. Solanki and C.M. Pandey