Advice for Veterinary Professionals 175
Table 11.2.Examples of nutraceuticals* and herbal supplements that may aid behaviour therapy. (Adapted from DePorteret al., 2016.)SupplementHow does it workIndicationsPrecautionsAlpha CasozepineA nutraceutical derived fromcasein, a protein in cow’s milkReported to have anxiolytic effectssimilar to benzodiazepinesFear, anxiety, stressNone reportedTryptophanAn essential amino acid (one ofthe building blocks of proteins) and the dietary precursor of serotoninMay increase available levels ofserotonin or enhance its transmissionAnxiety, stressMay increase the risk ofserotonin syndrome‡ if usedconcurrently with drugs that increase serotonin levelsTheanineAn amino acid found in greentea that has a chemical structure similar to glutamateMay block the effects of glutamate andincrease GABA. An advantage is that it is highly palatable to catsFear, anxiety, stressNone reportedDocosahexanoic acid (DHA)and Eicosapentaenoic acid (EPA)
Polyunsaturated fatty acidsEssential for early brain and retinaldevelopment, and to help maintain brain function in adultsFor healthy brain andretinal development in kittens and to improve cognitive function in senior catsAvoid high doses, which mayresult in gastrointestinal effects, weight gain, altered immune function and poor wound healing (Lennox, 1993)ValerianHerbValeriana officinalisUsually prepared with other herbsin either a tablet or liquid form for oral administration or in a spray or diffuser for environmental use. Can have sedative propertiesAnxiety, fear, stress,excitability, timidity, and car sicknessCatnipHerbNepeta catariaThe active ingredient is the essential oilnepetalactone which affects the CNS via the olfactory bulb
Does not affect all cats (only around50-70%) and effects can be variable with affected cats showing a wide range of behavioursEncouragement to playand aid enrichment. May be used to encourage scratching on a suitable surfaceMay cause increasedarousal resulting in short term aggression. Catnip intoxication has been reported*A nutraceutical is a food or food derivative that is said to have medicinal or health-giving properties.‡Serotonin syndrome is a term used to describe a potentially fatal condition that can arise if serotonin levels or availability are excessively increased.