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Meds and Your Mood
24 GUIDE TO WELLNESS CR.ORG
Never stop
a regular
prescription
drug
without
discussing
it with your
doctor.
- BETA-BLOCKERS
AND ACE INHIBITORS
(BLOOD PRESSURE
DRUGS) metoprolol,
atenolol, enalapril,
and quinapril. - ANTIDEPRESSANTS
sertraline (Zoloft
and generic),
citalopram (Celexa
and generic),
bupropion
(Wellbutrin and
generic), and
amitriptyline.
3. ANTI-ANXIETY
DRUGS alprazolam
(Xanax and generic),
clonazepam
(Klonopin and
generic), diazepam
(Valium and
generic), and
lorazepam (Ativan
and generic),
as well as the
sedative zolpidem
(Ambien and
generic).
4. OPIOIDS
hydrocodone
combination meds
(Lorcet, Norco,
Vicodin, and more,
and generic), and
tramadol (ConZip).
5. CORTICOSTEROIDS
prednisone and
others.
6. OVER-THE-
COUNTER PROTON
PUMP INHIBITORS
omeprazole
(Prilosec, Zegerid,
and generic) and
esomeprazole
(Nexium and
generic), as well
as the antacids
ranitidine (Zantac
and generic)
and famotidine
(Pepcid and
generic).
7. ALLERGY
AND ASTHMA
MEDICATIONS
over-the-counter
cetirizine (Zyrtec
and generic) and
the prescription
drug montelukast
(Singulair).
8. ANTICONVULSANTS
gabapentin
(Neurontin and
generic) and
topiramate
(Topamax and
generic).
9. HORMONES
estradiol
(Delestrogen,
Elestrin, EstroGel,
and generic)
and finasteride
(Proscar, Propecia,
and generic).
9 Drug Types That May
Cause Depression
Be aware that these meds can affect mood
Watch Your New Meds
Drug-related depression
symptoms can crop up at any
time, but you’re most likely
to see them within the first
month of use, Olfson says.
So every time your physician
prescribes a new medication,
ask whether depression is
a possible side effect. If so, jot
down any mood-related side
effects you notice. Note the
day and time when symptoms
occur, and whether they’re
recurring. Report any symp-
toms that persist for more
than a week or two to your
doctor immediately.
Ask About a Change
If medication seems to be
the cause, talk to your doc-
tor. Sometimes the fix is as
simple as cutting the dosage.
For instance, if your doctor
prescribes a lower but still
effective dosage of a blood
pressure- lowering beta-
blocker and your depres sion
eases, that may be a sign
that your mood changes
were drug-related, says Ana
María López, M.D., president
of the American College
of Physicians.
If the lower dosage makes
little difference in mood or
doesn’t work well for your
physical health, your doctor
should switch you to another
class of drugs, says Philip
Muskin, M.D., professor of
psychiatry at Columbia Uni-
versity Irving Medical Center.
Depending on your health
status, you may be able to
stop taking a medication alto-
gether—but never stop a regu-
lar prescription drug without
discussing it with your doctor.
Explore Lifestyle Fixes
If you can’t reduce a dosage
or stop taking a medication,
talk to your doctor about
other strategies. “We can
talk with a patient about life-
style changes that may help—
for example, starting a daily
walking routine if you’ve
been sedentary, because exer-
cise can help improve mood,
or having you increase your
social connections, because
a sense of belonging can
also improve mood,” López
says. One recent study found
that 28 percent of sedentary
people being treated for
depression reported improve-
ments three months after
beginning a moderate or brisk
walking routine.
The next step might be talk
therapy—or, if your symptoms
linger, antidepressant medi-
cation. Keep in mind that
certain antidepressants may
trigger anxiety.