Science 28Feb2020
was ameliorated by administration of propi- onate during pregnancy (Fig. 3D). Heart rate and body temperature after weaning, an ...
Kimuraet al.,Science 367 , eaaw8429 (2020) 28 February 2020 8of12 Fig. 6. Propionate supplemen- tation of pregnant mothers resul ...
compared with control LFi offspring (Fig. 6B and fig. S22, B and C). HFD-induced glucose intolerance and insulin resistance were ...
the pregnancy period (table S3). Offspring were reared by CMF-fed conventional foster mothers for 4 weeks. Over the course of th ...
SCFA was determined using external standard calibration over an appropriate concentra- tion range. Commensal bacteria compositio ...
< 0.05 were considered statistically significant. False discovery rates (qvalue) of the metabolo- mics and 16SrDNA amplicon s ...
RESEARCH ARTICLE ◥ PLANT SCIENCE Pectin homogalacturonan nanofilament expansion drives morphogenesis in plant epidermal cells Ka ...
and fig. S5B), which is the limit of our reported lateral resolution. In the periclinal walls, in contrast, we did not detect a ...
FEM implementation of the model To test the above hypothesis, we developed a 3D nonlinear FEM model that simulates lobe growth a ...
for the PME5oe and PMEI3oe lines, where anticlinal wall thickness was found to be more homogeneous between lobed and straight po ...
filaments. The HG nanofilaments appear to be absent in the periclinal walls, which sug- gests that HG forms an amorphous mesh, a ...
IMMUNOLOGY Structure of the secretory immunoglobulin A core Nikit Kumar, Christopher P. Arthur, Claudio Ciferri, Marissa L. Mats ...
of IgA to the Fc core and the addition of the SC would result in the formation of a more rigid molecule amenable to high-resolut ...
Fc2 contributed two parallelb-strands each, extending the bottom and top sheets, respec- tively, of the twisted JCb-sandwich (Fi ...
Kumaret al.,Science 367 , 1008–1014 (2020) 28 February 2020 4of7 Fig. 4. Mechanism of IgA oligomerization.Top view of (A) dimeri ...
dimer. The interaction with D1 was noncovalent and involved all three complementarity deter- mining region (CDR)–like loops, whe ...
tailpiece-binding residues are solvent acces- sible (Fig. 6, A and B). Expanding on the hy- pothesis of Stadtmuelleret al.( 15 ) ...
these fundamentally important questions in mucosal immunity. REFERENCES AND NOTES P. de Sousa-Pereira, J. M. Woof,Antibodies 8 ...
REPORT ◥ IMMUNOLOGY Structural insights into immunoglobulin M Yaxin Li1,2, Guopeng Wang^3 , Ningning Li2,3, Yuxin Wang1,2, Qinyu ...
The J-chain was identified almost 50 years ago as an integral subunit of secretory IgA and IgM ( 15 , 16 ). Guided by the disulf ...
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