Science - USA (2020-05-22)
connect substrate binding by R88 and R322 with titratable regulatory sites within the trans- membrane domains. The R88 cluster ( ...
The allosteric regulation of VGLUTs by H+ provides a mechanism to prevent glutamate efflux to the synaptic cleft when VGLUTs tra ...
of pH and Cl−that has been observed in the literature ( 4 , 6 , 11 , 28 ). It has been proposed that a VGLUT-associated Cl−condu ...
R. T. Fremeau Jr.et al.,Neuron 31 , 247–260 (2001). S. M. Wojciket al.,Proc. Natl. Acad. Sci. U.S.A. 101 , 7158– 7163 (2004). A ...
CELL BIOLOGY Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells Š. Bálint^1 , S. Mü ...
killing of K562 cells by 30% (n=5donors,P< 0.001), whereas knockout of another similarly enriched protein, galectin-1, by 90% ...
3Bandfig.S16).Thus,SMAPsfromCTLshavea glycoprotein shell that includes TSP1. To further investigate the structure of SMAPs, we u ...
Bálintet al.,Science 368 , 897–901 (2020) 22 May 2020 4of5 Fig. 3. SMAPs shell was rich in glycoproteins, TSP1, and organic mate ...
cells may become important in situations of transient and multiple interactions, where de- livery might be less precise. SMAPs m ...
S hanghai,acityofinnovation,richcultureandecology,isnowdevelopingintoanextraordinary modernmetropolis,andbecomingaglobalcenterof ...
SCHOOL MAIN FORUM SCHOOL MAIN FORUM Shanghai University League’s Forum for Interna- tional Young Scholars — Elec.Forum @FUDAN Sh ...
online @sciencecareers.org Confusedaboutyournext careermove? ScienceCareers.org/booklets Download Free Career Advice Booklets! ...
online @sciencecareers.org Jefferson Science Fellowship Program The National Academies of Sciences, Engineering, and Medicine is ...
My husband and I had started fer- tility treatments during my postdoc years, unable to conceive on our own. The process was exha ...
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