BNF for Children (BNFC) 2018-2019

Systemic candidiasis where other antifungal drugs inappropriate or ineffective ▶BY MOUTH ▶Child: 5 mg/kg once daily (max. per do ...

▶Rare or very rare ▶With oral useErectile dysfunction.hearing impairment. leucopenia.sensation abnormal.serum sickness.urinary f ...

lSIDE-EFFECTS ▶Common or very commonAcute kidney injury. agranulocytosis.alopecia.anaemia.anxiety.arrhythmias .asthenia.bone mar ...

Cryptococcal meningitis (adjunct to amphotericin) ▶BY INTRAVENOUS INFUSION, OR BY MOUTH ▶Neonate: 50 mg/kg every 12 hours. ▶Chil ...

Mild to moderate disease Co-trimoxazole p. 350 in high dosage is the drug of choice for the treatment of mild to moderate pneumo ...

lCAUTIONSAnaemia (treat severe anaemia before starting) .avoid in Acute porphyrias p. 603.cardiac disease.G6PD deficiency.pulmon ...

lHANDLING AND STORAGEPentamidine isetionate is toxic and personnel should be adequately protected during handling and administra ...

‘special-order’manufacturers or specialist importing companies). Strongyloidiasis AdultStrongyloides stercoralislive in the gut ...

lPREGNANCYEmbryotoxic inanimalstudies, avoid if possible. lBREAST FEEDINGNo information available. lHEPATIC IMPAIRMENT Dose adju ...

10 days, given alone for chronic infections or following metronidazole or tinidazole treatment. Foramoebic abscessesof the liver ...

occur. Injection should befiltered immediately before administration using afilter of 5 microns or less. lMEDICINAL FORMS There ...

Key to recommended regimens for prophylaxis against malaria Codes for regimens Details of regimens for prophylaxis against malar ...

Country Comments on risk of malaria and regional or seasonal variation Codes for regimens Colombia Low risk in rural areas below ...

Key to recommended regimens for prophylaxis against malaria Codes for regimens Details of regimens for prophylaxis against malar ...

Country Comments on risk of malaria and regional or seasonal variation Codes for regimens Philippines Low risk in rural areas be ...

2 months of age. It can also be used during pregnancy and breast-feeding. However, ingestion should be avoided, therefore breast ...

likely to be more than 24 hours away from medical care. Self- medication should beavoidedif medical help is accessible. In order ...

For a radical cure, primaquine [unlicensed] is then given to children over 6 months of age; specialist advice should be sought f ...

MonitoringManufacturer advises monitor ECG and plasma-potassium concentration in moderate to severe renal impairment. lMONITORIN ...

Chloroquine lINDICATIONS AND DOSE Prophylaxis of malaria ▶INITIALLY BY MOUTH USING SYRUP ▶Child 4–5 weeks (body-weight up to 4.5 ...