BNF for Children (BNFC) 2018-2019

are required. Spacer devices increase airway deposition and reduce oropharyngeal deposition. Corticosteroids, replacement therap ...

CONTRA-INDICATIONS, FURTHER INFORMATION For further information on contra-indications associated with intra-articular, intraderm ...

.received more than 40 mg prednisolone (or equivalent) daily for more than 1 weekor 2 mg/kg daily for 1 weekor 1 mg/kg daily for ...

eiiiiF 436 Dexamethasone 21-Dec-2017 lINDICATIONS AND DOSE Physiological replacement ▶BY MOUTH, OR BY SLOW INTRAVENOUS INJECTION ...

▶Martapan(Martindale Pharmaceuticals Ltd) Dexamethasone (as Dexamethasone sodium phosphate) 400 microgram per 1 mlMartapan 2 mg/ ...

lSIDE-EFFECTS ▶Uncommon ▶With rectal useSkin discolouration ▶Frequency not known ▶With oral useDyslipidaemia.fatigue.hypotension ...

Methylprednisolone (as Methylprednisolone sodium succinate) 125 mgSolu-Medrone 125 mg powder and solvent for solution for inject ...

lUNLICENSED USEPrednisolone rectal foam not licensed for use in children (age range not specified by manufacturer). IMPORTANT SA ...

ENZYME INHIBITORS Ketoconazole 20-Jul-2017 lDRUG ACTIONAn imidazole derivative which acts as a potent inhibitor of cortisol and ...

lHEPATIC IMPAIRMENTUse with caution in hepatic impairment (delayed response). lPATIENT AND CARER ADVICE Driving and skilled task ...

resulting tissue damage has both short-term and long-term adverse effects on health; this can result in retinopathy, nephropathy ...

renal disease, thyroid disorders, coeliac disease, Addison’s disease or gastroparesis. A review of the child’s injection sites s ...

Insulin preparations Insulin preparations can be broadly categorised into three groups based on their time-action profiles: shor ...

gThe dose of standard-release metformin hydrochloride should be increased gradually to minimise the risk of gastro- intestinal s ...

.Once blood glucose falls to 14 mmol/litre,glucose intravenous infusion 5 %or 10 %should be added to the fluids. .The insulin in ...

should be discontinued 24 hours before the procedure. Children having minor surgery lasting less than 2 hours may stop their met ...

BLOOD GLUCOSE LOWERING DRUGS› BIGUANIDES Metformin hydrochloride 06-Jun-2017 lDRUG ACTIONMetformin exerts its effect mainly by d ...

eiiiiF 452 Glibenclamide lINDICATIONS AND DOSE Type 2 diabetes mellitus ▶BY MOUTH ▶Child 12–17 years:Initially 2. 5 mg daily, ad ...

INSULINS Insulins f IMPORTANT SAFETY INFORMATION NHS IMPROVEMENT PATIENT SAFETY ALERT: RISK OF SEVERE HARM AND DEATH DUE TO WITH ...

morning rise in blood-glucose concentration despite optimised multiple-injection regimens. Patients on subcutaneous insulin infu ...