Medical Microbiology

138 2 BasicPrinciplesofImmunology

Table2. 13 Continued:ImportantCDAntigens

Designation

(alternatives)

Cellswhichexpressthe

antigen

Functions

CD1 02 (ICAM-2)

(intercellularcell

adhesion

molecule)

Restinglymphocytes,mono-

cytes,endothelialcells

(inwhichexpressionismost

pronounced)

BindsCD11a/CD1 8 (LFA-1),but

notCD11b/CD1 8 (MAC-1)

CD1 06 (VCAM-1)

(vascularcell

adhesion

molecule)

Endothelialcells Adhesionmolecule;ligandfor

VLA-4(verylateantigen)

CD1 15 Monocytes,macrophages Receptorforthemacrophage

colony-stimulatingfactor

(M-CSF)

CD1 16 Monocytes,neutrophils,and

eosinophils,endothelium

achainofthereceptorforthe

granulocyte-macrophagecolony-

stimulatingfactor(GM-CSF)

CD1 17 Hematopoieticprecursorcells Receptorforstemcellfactor

(SCF)

CD1 18 Widespread Receptorforalpha/betainter-

ferons(IFNa/b)

CD1 19 Macrophages,monocytes,

Bcells,endothelium

Receptorforgammainterferon

(IFNc)

CD120a Hematopoieticand

nonhematopoieticcells

Mostpronouncedonepithelial

cells

Acknowledgment

TheexperteditingandtranslatinghelpofNicolaHarrisPhDisgratefully

acknowledged.

2

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Kayser, Medical Microbiology © 2005 Thieme

All rights reserved. Usage subject to terms and conditions of license.