Medical Microbiology

Table 1 2. 4 GenitalTract(venerealdiseases)

Infection Mostimportant

pathogens

Laboratorydiagnosis

Gonorrhea Neisseriagonorrhoeae Microscopy(sendtwoslidesto

thelaboratory,forgramstaining

andIF);culture(swabinspecial

transportmedium);rapidanti-

gendetectionwithantibodiesin

swabmaterial;PCR(kitavailable

todetectC.trachomatissimulta-

neously)

Syphilis(lues) Treponemapallidum

(ssp.pallidum)

Microscopy(darkfield)ofmate-

rialfromstageIandIIlesions.

Serology(seep. 321 forbasic

diagnostics)

Lymphogranuloma

venereum

Chlamydiatrachomatis

(Lserovars)

Microscopy(directIF)ofpus;

cellcultureorPCR

Ulcusmolle

(softchancre)

Haemophilusducreyi Microscopyofpus.

Culture(verydifficult)

Granulomainguinale Calymmatobacterium

granulomatis

Microscopyofscrapingsor

biopsymaterial(lookfor

Donovanbodies);culture

(embryonatedhen’seggor

specialmediums)

GenitalTract 637

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Kayser, Medical Microbiology © 2005 Thieme