0071643192.pdf

CHAPTER 9

Hematology, Oncology,

Allergy, and

Immunology

Alex Ho, MD

Anemia 453

Hemolytic Anemia 454

HEREDITARYSPHEROCYTOSIS 454

THALASSEMIA 455

G6PD DEFICIENCY 456

SICKLECELLDISEASE 457

IMMUNE-MEDIATEDHEMOLYTICANEMIA 459

MICROANGIOPATHICHEMOLYTICANEMIA 461

Polycythemia 461

Disorders of Hemostasis and Clotting Cascade 462

PRIMARYHEMOSTASIS 462

SECONDARYHEMOSTASIS 462

THROMBOCYTOPENIA 462

DISSEMINATEDINTRAVASCULARCOAGULATION 465

VONWILLEBRANDDISEASE 466

HEMOPHILIA 467

Anticoagulation and Antiplatelet Agents 468

WARFARIN 468

UNFRACTIONATEDHEPARIN 468

LOW-MOLECULAR-WEIGHTHEPARIN 469

DIRECTTHROMBININHIBITORS 470

ASPIRIN 470

THIENOPYRIDINES 470

GLYCOPROTEINIIB/IIIAINHIBITORS 471

Dyshemoglobinemias 471

METHEOMOGLOBINEMIA 471

SULFHEMOGLOBINEMIA 472