Medicinal Chemistry

(Jacob Rumans) #1
DESIGNING DRUG MOLECULES TO FIT RECEPTORS 167


  1. Conjugate addition to an α,β-unsaturated carbonyl group

  2. Cope rearrangement

  3. Diels–Alder reaction

  4. Friedel–Crafts alkylation

  5. Grignard addition

  6. Malonic ester synthesis

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