Nursing Diagnoses in Psychiatric Nursing Care Plans and Psychotropic Medications

(^464) AripiprazoleOlanzapineThe effects of: Are increased by:Chlorproma-zine^ ●^ PSYCHOTROPIC MEDICATIONS Beta-blockers, Fluvoxamine and other Ketoconazole and inhibitorspotential CYP-2D6 fl u o x e t i n e , p a r -paroxetineinhibitors; quinidine, other CYP-3A4 CYP-1A2 inhibitors, fl u o x e t i n eoxetine, or other Carbamazepine, Carbamazepine and Are decreased by:Centrally acting other CYP-1A2 rifampinfamotidine, valproateomeprazole, inducers, anticholinergics result in: Decreased effects of Increased CNS depression Increased effects of Concurrent use may antihypertensives. depressants. Increased hypotension with Increased CNS depression hypotension with agonists. Increased levodopa and dopamine antihypertensives. hypotension with thiazide depressants.with alcohol or other CNS beta-blockers; excessive sedation and hypoten-sion with meperidine; decreased hypotensive effect of guanethidine; decreased effect of oral anticoagulants; decreased or increased phenytoin levels; increased orthostatic with alcohol or other CNS

2 2506_Ch27_447-471.indd 0464 506 Ch 27 447 - 471 .indInteractionsdRisperidoneQuetiapine 0464 Clozapine, fl uoxetine, Cimetidine; keto-paroxetine, or ritonavirother CYP-3A4 erythromycin, or azole, fl uconazole, conazole, itracon-inhibitors CarbamazepinePhenytoin, thioridazine Decreased effects of Decreased effects of levodopa and dopamine effects of clozapine and valproate. Increased CNS depression with alcohol or other CNS depressants. Increased hypotension with antihypertensives. agonists. Increased with antihypertensives. Increased anticholinergic effects with anticholiner-gic agents.diuretics; Increased CNS depression with alcohol or other CNS depressants. Increased hypotension antihypertensives.depressants. Increased alcohol or other CNS CNS depression with agonists. Increased levodopa and dopamine hypotension with 1 10/1/10 9:39:47 AM 0 / 1 / 10 9 : 39 : 47 AM