iii) Finally, enzymatic removal of a proton from C9 forms the C8-C9 double bond
leading to lanosterol.
CH 3
H 3 C
CH 3
CH 3
H 3 C
CH 3
CH 3
HO H
H
H
CH (^318)
(^1317)
14
8
10 9
5
Protosteryl cation
B
CH 3
CH 3
CH 3
H
H
CH 3
CH 3
CH 3
CH 3
3 C
HO^9814
10 13 17
18
Lanosterol
- The remaining steps to cholesterol involve loss of three carbons through 19
oxidation-reduction steps:
H
H 3 C
HC H 3 C
19
3
H 3 C
HO CH
3 Lanosterol
CH (^3) H
Cholesterol
- the basis of the same fundamental principles and
8.16 SU
Summ
CH 3
HO
steps H H
Biosynthetic reactions occur on
reaction pathways in organic chemistry.