Textbook of Personalized Medicine - Second Edition [2015]

45

Role of Biochip/Microarray Technology

in Personalized Medicine

Microarray technology not only helps to make sense of the vast amount of genomic
information but also enables its application to the patient by early detection of dis-
ease and prediction of drugs response in individuals. Although some problems of
standardization and integration with electronic records remain, microarrays are
promising for effi cient, cost-effective, and personalized approaches to human
health care. Role of biochip/microarray technology in personalized medicine is
shown in Fig. 2.2.

Applications of Biochip/Microarray Technology

in Personalized Medicine

Selected applications of biochip technology relevant to this report are listed in
Table 2.2.
Microarrays allow scientists to look at very subtle changes in many genes at one
time. They provide a snapshot of what genes are expressed or active, in normal and
diseased cells. When normal cells or tissues are compared to those known to be
diseased, patterns of gene expression can emerge, enabling scientists to classify the

Molecular

Diagnostics

Personalized

Medicine

Biochips

Microarrays

Pharmacogenetics

Pharmacogenomics

Biomarkers

Nanobiotechnology

Proteomics

Sequencing

Personalized

drug discovery

Point-of-Care

diagnostics

© Jain PharmaBiotech

Fig. 2.2 Role of biochip/microarray technology in personalized medicine

Biochips and Microarrays