14-9the test statistics for main effects and interactions have been constructed properly using
Equations S14-9 through S14-11.14-7.4 Addition of Center Points to a 2kDesign (CD Only)A potential concern in the use of two-level factorial designs is the assumption of linearity in the
factor effects. Of course, perfect linearity is unnecessary, and the 2ksystem will work quite well
even when the linearity assumption holds only approximately. However, there is a method of
replicating certain points in the 2kfactorial that will provide protection against curvature as well
as allow an independent estimate of error to be obtained. The method consists of adding center
pointsto the 2kdesign. These consist of nCreplicates run at the point xi0 (i1, 2,... , k). One
important reason for adding the replicate runs at the design center is that center points do not
affect the usual effects estimates in a 2kdesign. We assume that the kfactors are quantitative.
To illustrate the approach, consider a 2^2 design with one observation at each of the
factorial points ( , ), (, ), ( ,), and (,) and nCobservations at the center points
(0, 0). Figure S14-3 illustrates the situation. Let yFbe the average of the four runs at the fourTable S14-5 Minitab Analysis of Variance for the Breaking Strength Data in Table S14-1 Where
Operators Are Fixed and Machines Are Random (Mixed Model)
Analysis of Variance (Balanced Designs)
Factor Type Levels Values
Operator fixed 3 A B C
Machine random 4 1234Analysis of Variance for Strength
Source DF SS MS F P
Operator 2 26.333 13.167 2.21 0.190
Machine 3 24.333 8.111 2.16 0.145
Operator*Machine 6 35.667 5.944 1.59 0.234
Error 12 45.000 3.750
Total 23 131.333Figure S14-3 A 2^2
design with center
points.yBA–1
0
+1+10
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