Typography - Getting The Hang Of Typography

Users will react to type differently depending on where it is placed on the
page. Type placed in the main body copy will have greater importance than
type placed in a sidebar, with all other factors being equal. Large type in the
sidebar will still call attention to itself and could move itself up in the
pecking order. One needs to carefully balance type in the main body and
sidebar area based on how you want the user to digest the information you
present.