Dairy Ingredients in Infant and Adult Nutrition Products 517
needs resulted in signifi cant nutritional
defi ciencies and unacceptably high infant
mortality. Infant formula innovations across
the centuries are given in Table 20.3 (Hansen
and Diener, 1997 ; Benson and Masor, 1994 ;
Committee on the Evaluation of the Addition
of Ingredients New to Infant Formula, 2004 ).
As shown in Table 20.4 , the milk protein
combinations commonly used in commercial
infant formulas, while adequate in supplying
protein nutrition, still do not replicate the
protein composition of breast milk. The more
esoteric and complex benefi ts derived from
functionality, a key challenge the industry
faces is delivering innovation within regula-
tory, cost, and benefi t expectations.
Innovations in Infant Nutrition
The fi rst intentionally designed infant formu-
las were produced in response to problems
generated by the use of condensed skim milk
as a mother ’ s milk replacement in the late
19th and early 20th centuries. Differences
in composition between bovine and human
milks (Table 20.2 ) and vitamin and mineral
Table 20.2. General composition of human and cow ’ s milk.
Contents Human milk Cow ’ s milk
Fat
Total (g/100 ml) 4.2 3.8
Fatty acids < 8 ° C * Trace 6
Polyunsaturated fatty acids (%) 14 3
Protein (g/100 ml)
Total 1.0 – 1.3 3.0 – 3.3
Casein 0.3 2.5
Whey 0.7 0.5
Casein : whey ratio 40 : 60 80 : 20
Carbohydrate (g/100 ml)
Lactose 7.0 4.8
Oligosaccharides 0.5 0.005
Minerals (g/100 ml) 0.2 0.7
* Chain length, in carbons
Source: http://www.unu.edu/unupress/food/8F174e/8F174E04.htm
Table 20.3. Infant formula developmental timeline.
Future Will depend on understanding of disease states, nutrient bioavailability, etc.
2000s Long - chain polyunsaturated fatty acids (LCPUFAs) introduced
Choline fortifi cation
Probiotics/prebiotics
Late 1990s Nucleotide fortifi cation
1980s Taurine fortifi cation
Infant Formula Act
1960s Iron fortifi cation considered
Renal solute load considered
Concentrated liquid formula
Whey : casein ratio similar to human milk
1940s Hypoallergenic formula for allergy management
Protein content of the formula considered
1920s Commercially available soy formula
1900s Carbohydrate additive
Moores and Ross Milk CO makes Franklin Infant Food — forerunner of Similac
Human milk fat simulated in SMA formula
1850s Human milk simulation by adding carbohydrates to cow ’ s milk
1750s Cow ’ s milk dilution