Comparative and Veterinary Pharmacology

Kim MS, Liu DQ, Strauss JR, Capodanno I, Yao Z, Fenyk-Melody JE, Franklin RB, Vincent SH (2003) Metabolism and disposition of ge ...

Mickelson JR, Gallant EM, Litterer LA, Johnson KM, Rempel WE, Louis CF (1988) Abnormal sarcoplasmic reticulum ryanodine receptor ...

receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains. Toxicol Appl Pharmacol 155:82–95 Poland A, Glove ...

Schulz-Utermoehl T, Bennett AJ, Ellis SW, Tucker GT, Boobis AR, Edwards RJ (1999) Polymor- phic debrisoquine 4-hydroxylase activ ...

Walraven JM, Barker DF, Doll MA, Hein DW (2007) Tissue expression and genomic sequences of rat N-acetyltransferasesrNat1,rNat2,r ...

Drug Delivery Systems in Domestic Animal Species David J. Brayden, Emilie J. M. Oudot, and Alan W. Baird Contents 1 Introduction ...

pharmacokinetic, pharmacodynamic and physiological differences, and distinct market drivers for drug classes used in companion a ...

those of human medicine and this enables premium products to be developed. Supplied on an individual basis, companion animal pro ...

requirement for unique device specifications for each species. Nevertheless, there are recent examples of re-formulated human SS ...

membranes passively, including anti-parasiticides, some antibacterials, steroid hor- mones, and growth promoters. These agents a ...

ensure maintained drug absorption from the upper small intestine (Streubel et al. 2006 ). Oral i.r. devices have been successful ...

then released for approximately 135 days. The history of the development of the device components, together with the influence o ...

tablets for dogs (Thombre 2004 ). Examples of flavoured chewable tablets designed for dogs include beef-flavoured ivermectin/pyr ...

Inhaled drugs for small animals are, however, used to treat local conditions including canine bronchitis, kennel cough and felin ...

3.3 Topical Formulations and Transdermal Patches Topical formulations including dusting powders, creams, ointments, pastes, pour ...

a b c Fig. 2Mode of action of spot-on anti-parasitic drugs (e.g. fipronil or imidacloprid). (a) Oil-based spot-on administered t ...

Transdermal patches delivering a range of passively-absorbed lipophilic drugs have been successfully developed for human medicin ...

3.4 Intravaginal Delivery for Fertility Regulation Non-human primates are widely used in research on reproductive management. Re ...

in order to manage ovarian dysfunction inpostpartumdairy cows (Kim et al. 2004 ). The PRID 1 device has evolved for successful i ...

administration is during the dry period, when it is easier to maintain high concen- trations in the teat and gland over several ...