Neuromuscular blockage may increase when aminoglycosides are given to
patients who have received anesthetics (halogenated hydrocarbon) or citrate-
anticoagulated blood through massive transfusions. Methoxyflurane (Penthrane)
and polymyxins, given parenterally also increase the possibility for neuromus-
cular blockage as well as kidney toxicity.
In addition, patients who are treated with aminoglycides can have interactions
with the following medications:- Amphotericin B parenteral (Fungizone)
- Aspirin
- Bacitracin parenteral
- Bumetanide parenteral aspirin
- Bacitracin
- Parenteral bumetanide (Bumex)
- Cephalothin (Keflin)
- Cisplatin (Platinol)
- Cyclosporine (Sandimmune)
- Ethacrynate parenteral (Edecrin)
- Furosemide parenteral (Lasix)
- Paromomycin (Humatin)
- Polymyxins
- Streptozocin (Zanosar)
- Vancomycin (Cancocin)
Aminoglycosides, Nursing Diagnosis,
and Collaborative Problems
Patients who receive aminoglycosides may also experience nephrotoxicty (kid-
ney), neurotoxicity (muscle twitching, numbness or seizures), and hypersensitivity.
Here are the common nursing diagnosis related to a patient who is receiving
aminoglycosides.- Sensory-perceptual alterations: auditory ototoxicity (loss of hearing and
tinnitus), vestibular ototoxicity (dizziness and loss of balance) and periph-
eral neuritis (tingling of the fingers and toes)
(^230) CHAPTER 13 Antimicrobials—Fighting Infection