Disease External eye findings Fundoscopic findings
Leptospirosis
(Weil’s syndrome)
l Conjunctival suffusion (often dramatic
hemorrhagic )
l Conjunctival discharge
l Subconjunctival hemorrhage
l Hypopyon (a small hypopyon may
require SL evaluation)
l Scleral icterus +/–
SL:
l Mutton fat keratic precipitates
l Uveitis (anterior or posterior)l Retinal hemorrhage
l Retinal exudates
l Optic neuritisDisease External eye findings Fundoscopic findings
Rocky Mountain
spotted fever
(RMSF)
l Conjunctivitis with papillae
l Conjunctival petichiae
l Subconjunctival hemorrhage
l Corneal ulceration
SL:
l Panuveitis
l Iritisl Retinal hemorrhage
l Retinal exudates
l Optic nerve pallor
l Roth spotsDisease External eye findings Fundoscopic findings
Tularemia
(oculoglandular)
l Conjunctivitis with purulent discharge
l Conjunctival nodules (1–5 mm)
l Chemosis
l Necrosis of conjunctivae
l Eyelid edema
l Periorbital edema
l Eyelid ulceration
SL:
l Corneal edema
l Peripheral corneal infiltrates
(relatively rare, but have a very high
specificity when present)
l Nodules along the limbusl Optic neuritisFigure 3 Optic neuritis (see
color insert).Disease External eye findings Fundoscopic findings
Hantavirus pulmonary
syndrome (HPS)
l Conjunctival suffusionSL:
l Nonel None68 Cunha et al.