Quick Review Cards for Medical Laboratory Science

Hepatitis Tests Immunology Review 403

TEST

Hepatitis A
Total anti-HAV

IgM anti-HAV

HAV RNA

Hepatitis B
HBsAg

HBeAg

Total anti-HBc

IgM anti-HBc

Anti-HBe

Anti-HBs

SIGNIFICANCE

Past infection & immunity

Acute infection

Current infection

Acute or chronic infection, infectivity

Acute or chronic infection

Current or past infection or carrier

Current or recent infection

Recovery, reduced infectivity

Recovery & immunity

COMMENTS

Used to detect HAV in food & water.

1st serological marker to appear. Used to screen donor blood.

Pos should be confirmed by repeat testing & another assay

such as HBsAg neutralization or HBV DNA.

Indicates high degree of infectivity.

Predominantly IgG, which persists for life.

1st ab to appear. Useful for detecting HBV infection when

HBsAg is no longer detectable (“window period”). Used to

screen blood donors.

Ab that develops following immunization.

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