Hepatitis Testscontinued Immunology Review 404
TEST
HBV DNA
Hepatitis C
Anti-HCV
HCV RNA
Hepatitis D
(delta hepatitis)
IgM anti-HDV
IgG anti-HDV
HDV RNA
Hepatitis E
SIGNIFICANCE
Current infection
Acute, chronic, or previous infection
Current infection
Acute or chronic infection
Recovery or chronic infection
Current infection
COMMENTS
Detectable 21 days before HBsAg. Used to monitor viral load &
therapy.
Pos should be confirmed by recombinant immunoblot assay
(RIBA) or molecular method.
Used for viral load testing, blood/organ donor screening. HCV
genotyping to determine optimal treatment.
HDV is a defective virus that can only occur in presence of HBV.
Marker of active viral replication. Used to monitor therapy.
Tests are currently not approved by FDA for use in U.S.
Most serological tests for hepatitis are by EIA or CIA. Molecular methods detect infections earlier.