Anticoagulant/Preservative Solutions Immunohematology Review 424
NAME ABBREVIATION RBC SHELF LIFE COMMENTS
Acid citrate-dextrose (Formula A) ACD-A 21 days Citrate prevents coagulation by chelating Ca2+.
Dextrose (glucose) supports ATP generation.
Used for apheresis.
Citrate-phosphate-dextrose CPD 21 days Higher pH preserves 2,3-DPG better. Better O 2
delivery.
Citrate-phosphate-double-dextrose CP2D 21 days Contains 100% more glucose than CPD.
Citrate-phosphate-dextrose with adenine CPDA-1 35 days Adenine increases ADP, which increases
synthesis of ATP. Contains more glucose to
sustain cells during longer storage.
