The Scientist - USA (2022 - Spring)

I still recall my disappointment one day in 2015. I received the tumor DNA sequencing results for one of my patients, whose canc ...

32 THE SCIENTIST | the-scientist.com © ANDREW SWIFT, ISO-FORM ing their level of CIN without affecting the other genetic abnorma ...

MARCH 2022 | ISSUE 1 | TS DIGESTSPRING 2022 | THE SCIENTIST 3333 came in 2010 from Robert Benezra and colleagues at MSK. They re ...

34 THE SCIENTIST | the-scientist.com Inflammation cGAS © ANDREW SWIFT, ISO-FORM cGAMP Nucleus STING Micronucleus Chromothripsis ...

SPRING 2022 | THE SCIENTIST 35 abnormal chromosomes. This process is known as chromothrip- sis, and researchers have recently id ...

36 THE SCIENTIST | the-scientist.com are in place to preserve the genomic integrity of the organ- ism, and they usually work. In ...

Did you know 69% of researchers don’t look for easy-to-use cellular imaging? 1 Do they just like doing it the hard way? It’s tim ...

CREDIT LINECREDIT LINE Could a tumor’s microbiome be the key to diagnosing and treating cancer? BY JEF AKST Cancer’s COMPOSITE F ...

COMPOSITE FROM: © ISTOCK.COM, CIPHOTOS; © ISTOCK.COM, SIBERIANARTCREDIT LINECREDIT LINE A s a postdoc at the Broad Institute of ...

40 THE SCIENTIST | the-scientist.com ADAPTED FROM SCIENCE , 371:EABC4552, 2021.; ILLUSTRATION BY © NICOLLE FULLER, SAYO STUDIO “ ...

Skin cancer Paraganglioma Esophageal cancer Gallbladder cancer Pancreatic cancer Colorectal cancer Bone cancer Cervical cancer O ...

42 THE SCIENTIST | the-scientist.com LEFT: PICTURE BY LARRY LUXNER; RIGHT: PICTURE BY LEORE GELLER FROM THE STRAUSSMAN LAB “But, ...

SPRING 2022 | THE SCIENTIST 43 LEFT: PICTURE BY LARRY LUXNER; RIGHT: PICTURE BY LEORE GELLER FROM THE STRAUSSMAN LAB entist agre ...

44 THE SCIENTIST | the-scientist.com MICRONOMA 44 TS DIGEST | the-scientist.com WHERE DOES THE TUMOR MICROBIOME COME FROM? Among ...

SPRING 2022 | THE SCIENTIST 45 MICRONOMA tion, applied for intellectual property to cover the approach and began the process of ...

46 THE SCIENTIST | the-scientist.com PICTURE BY DEBORAH NEJMAN FROM THE STRAUSSMAN LAB microbiomes are acutely aware that bacter ...

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EVOLUTIONARY J U MPS Long lambasted as junk DNA or genomic parasites, transposable elements turn out to be contributors to adapt ...

50 THE SCIENTIST | the-scientist.com © JULIA MOORE, WWW.MOOREILLUSTRATIONS.COM T he tale of the peppered moth (Biston betularia) ...