Internal Medicine

(Wang) #1

P1: OXT/OZN/JDO P2: PSB


0521779407-E-01 CUNY1086/Karliner 0 521 77940 7 June 4, 2007 21:10


562 Exfoliative Dermatitis Eyelid Lesions

■Physical – usually dermatitis is diffuse with involvement over many
areas, up to 100% body surface area
■Generalized erythroderma with desquamation
May be related to recent medication, viral exanthema, or other
infection
tests
■Skin biopsy to assess cause

differential diagnosis
■Dermatitis
■Psoriasis
■Cutaneous lymphoma
■Internal malignancy
■Lichen planus or other papulosquamous disease
Pityriasis rubra pilaris

management
■Assess cause and remove.
■Assess possible high–output cardiac failure.

specific therapy
Based on cause, but management of skin usually requires aggressive
topical therapy as well as systemic therapy

follow-up
Based on cause. It is important that biopsies are occasionally repeated
to rule out cutaneous lymphoma, even if they are initially inconclusive.
complications and prognosis
Based on cause. If related to medication, withdrawal and therapy with
appropriate measures usually leads to resolution. If T-cell lymphoma,
condition may be lifelong.

Eyelid Lesions.......................................


DEVRON H. CHAR, MD


history & physical
■Prior basal cell carcinoma (BCC) at any site, mandates a biopsy of
new lid lesions.
■Lash loss, a pearly, cavitated border, or a unilateral chronic ulceration
requires biopsy.
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