Small Animal Dermatology, 3rd edition

CHAPTER 25 HISTIOCYTIC PROLIFERATIVE DISORDERS 393 Fig. 25.11.Fine-needle aspirate cytology of a histiocytoma: pleomorphic roun ...

chapter 26 Hyperadrenocorticism, Canine............................ DEFINITION/OVERVIEW  Spontaneous hyperadrenocorticism (HAC) ...

CHAPTER 26 HYPERADRENOCORTICISM, CANINE 395  Iatrogenic HAC: Clinically indistinguishable from the naturally occurring disease ...

396 DISEASES/DISORDERS  Bacterial folliculitis (pyoderma): excess glucocorticoids predispose to skin infections from bacterial ...

CHAPTER 26 HYPERADRENOCORTICISM, CANINE 397 DIAGNOSTICS  Hemogram: eosinopenia, lymphopenia, neutrophilic leukocytosis, erythro ...

398 DISEASES/DISORDERS “Gold standard” for diagnosis of iatrogenic HAC: baseline cortisol levels will be below normal and will ...

CHAPTER 26 HYPERADRENOCORTICISM, CANINE 399 Can potentially demonstrate both increased cortisol production and decreased sensit ...

400 DISEASES/DISORDERS THERAPEUTICS Surgical Considerations  Hypophysectomy: described, but generally not recommended for treat ...

CHAPTER 26 HYPERADRENOCORTICISM, CANINE 401 ADH: Administer mitotane at highest tolerated dosage beginning with 50 mg/kg q24h ...

402 DISEASES/DISORDERS Must maintain daily (or BID) dosing for maintenance therapy, as opposed to twice weekly for mitotane Mo ...

CHAPTER 26 HYPERADRENOCORTICISM, CANINE 403 COMMENTS Patient Monitoring (see each drug)  Response to therapy.  Use periodic AC ...

404 DISEASES/DISORDERS Fig. 26.1.Naturally acquired hyperadrenocorticism in a 9-year-old female-spayed French bulldog. Note dis ...

CHAPTER 26 HYPERADRENOCORTICISM, CANINE 405 (a) (b) Fig. 26.3.(a)Lesions of calcinosis cutis of patient in Figures 26.1 and 26. ...

406 DISEASES/DISORDERS Fig. 26.4.Naturally acquired hyperadrenocorticism in a 10-year-old, male-castrate pit bull. Body conform ...

CHAPTER 26 HYPERADRENOCORTICISM, CANINE 407 Fig. 26.7.Focal patch of severe epidermal atrophy on the ventrum of the patient in ...

408 DISEASES/DISORDERS (a) (b) (c) Fig. 26.9.(a) Body conformation changes, diffuse alopecia, and (b) secondary deep bacterial ...

chapter Hyperadrenocorticism,^27 Feline Skin Fragility Syndrome DEFINITION/OVERVIEW  A disorder of multifactorial causes charac ...

410 DISEASES/DISORDERS CLINICAL FEATURES  May be associated with rat tail, pinnal folding, pot belly appearance (Figure 27.1). ...

CHAPTER 27 HYPERADRENOCORTICISM, FELINE SKIN FRAGILITY SYNDROME 411 or a sex hormone-secreting adrenal neoplasia; cortisol level ...

412 DISEASES/DISORDERS are better managed with divided twice-daily dosing; if receiving insulin twice daily, trilostane should b ...