433Kee K, Reijo Pera RA (2008) Human germ cell lineage differentiation from embryonic stem cells.
CSH Protoc 2008:pdb.prot5048. doi:10.1101/pdb.prot5048
Kehler J, Tolkunova E, Koschorz B, Pesce M, Gentile L, Boiani M, Lomeli H, Nagy A, McLaughlin
KJ, Scholer HR, Tomilin A (2004) Oct4 is required for primordial germ cell survival. EMBO
Rep 5(11):1078–1083. doi:10.1038/sj.embor.7400279, 7400279
Ketting RF (2011) MicroRNA biogenesis and function : an overview. Adv Exp Med Biol 700:1–
- doi:10.1007/978-1-4419-7823-3_1
Kimble JE, White JG (1981) On the control of germ cell development in Caenorhabditis elegans.
Dev Biol 81(2):208–219
Kimmel CB (1989) Genetics and early development of zebrafish. Trends Genet 5(8):283–288
King ML (2014b) Germ cell specification in Xenopus. In: Kloc M, Kubiak JZ (eds) Xenopus
development. Wiley, Hoboken, NJ, pp 75–100
Kirilenko P, Weierud FK, Zorn AM, Woodland HR (2008) The efficiency of Xenopus primordial
germ cell migration depends on the germplasm mRNA encoding the PDZ domain protein
Grip2. Differentiation 76(4):392–403. doi:10.1111/j.1432-0436.2007.00229.x
Kloc M, Bilinski S, Chan AP, Allen LH, Zearfoss NR, Etkin LD (2001) RNA localization and
germ cell determination in Xenopus. Int Rev Cytol 203:63–91
Kloc M, Bilinski S, Dougherty MT (2007) Organization of cytokeratin cytoskeleton and germ plasm
in the vegetal cortex of Xenopus laevis oocytes depends on coding and non-coding RNAs: three-
dimensional and ultrastructural analysis. Exp Cell Res 313(8):1639–1651. doi:10.1016/j.
yexcr.2007.02.018
Kloc M, Bilinski S, Dougherty MT, Brey EM, Etkin LD (2004a) Formation, architecture and
polarity of female germline cyst in Xenopus. Dev Biol 266(1):43–61
Kloc M, Bilinski S, Etkin LD (2004b) The Balbiani body and germ cell determinants: 150 years
later. Curr Top Dev Biol 59:1–36. doi:10.1016/S0070-2153(04)59001-4
Kloc M, Chan AP (2007) Centroid, a novel putative DEAD-box RNA helicase maternal mRNA, is
localized in the mitochondrial cloud in Xenopus laevis oocytes. Int J Dev Biol 51(8):701–706.
doi:10.1387/ijdb.072293mk
Kloc M, Dougherty MT, Bilinski S, Chan AP, Brey E, King ML, Patrick CW Jr, Etkin LD (2002)
Three-dimensional ultrastructural analysis of RNA distribution within germinal granules of
Xenopus. Dev Biol 241(1):79–93. doi:10.1006/dbio.2001.0488
Kloc M, Etkin LD (1994) Delocalization of Vg1 mRNA from the vegetal cortex in Xenopus
oocytes after destruction of Xlsirt RNA. Science 265(5175):1101–1103
Kloc M, Etkin LD (1998) Apparent continuity between the messenger transport organizer and late
RNA localization pathways during oogenesis in Xenopus. Mech Dev 73(1):95–106
Kloc M, Spohr G, Etkin LD (1993) Translocation of repetitive RNA sequences with the germ
plasm in Xenopus oocytes. Science 262(5140):1712–1714
Knaut H, Pelegri F, Bohmann K, Schwarz H, Nusslein-Volhard C (2000) Zebrafish vasa RNA but
not its protein is a component of the germ plasm and segregates asymmetrically before germ-
line specification. J Cell Biol 149(4):875–888
Knaut H, Steinbeisser H, Schwarz H, Nusslein-Volhard C (2002) An evolutionary conserved
region in the vasa 3′UTR targets RNA translation to the germ cells in the zebrafish. Curr Biol
12(6):454–466
Knaut H, Werz C, Geisler R, Nusslein-Volhard C, Tubingen Screen C (2003) A zebrafish homo-
logue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor. Nature 421(6920):279– - doi:10.1038/nature01338
Kocher-Becker U, Tiedemann H (1971) Induction of mesodermal and endodermal structures and
primordial germ cells in Triturus ectoderm by a vegetalizing factor from chick embryos. Nature
233(5314):65–66
Koebernick K, Loeber J, Arthur PK, Tarbashevich K, Pieler T (2010) Elr-type proteins protect
Xenopus Dead end mRNA from miR-18-mediated clearance in the soma. Proc Natl Acad Sci
U S A 107(37):16148–16153. doi:10.1073/pnas.1004401107
8 Mechanisms of Vertebrate Germ Cell Determination