457
Epithelial and
Nonepithelial Ovarian
Tumors
Chapter 46
Mitchell I. Edelson, MD
❍ Epithelial tumors include what histologic types?
(1) Serous (46%).
(2) Mucinous (36%).
(3) Endometrioid (8%).
(4) Clear cell.
(5) Brenner.
(6) Undifferentiated carcinomas.
❍ The lifetime risk and mean age for developing epithelial ovarian cancers is?
1.86% (1/70); 63 years.
❍ Characteristics of ovarian low malignant potential tumors include?
Tendency to remain confined to the ovary for long periods of time, occurrence predominantly in premenopausal
women, associated with an excellent prognosis. There is no need for adjuvant treatment even in those individuals
with advanced disease.
❍ Criteria for diagnosis of ovarian low malignant potential tumors include?
(1) Epithelial proliferation with papillary formation and pseudostratification.
(2) Nuclear atypia and increased mitotic activity.
(3) Absence of true stromal invasion.
❍ What percentage of invasive epithelial tumors spread beyond the ovary?
75% to 85%.
❍ Psammoma bodies are frequently associated with which type of ovarian tumors?
Serous.