Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical, Part 1

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7 Physical Exercise Can Spur Beneficial Neoangiogenesis

and Microvasculature Remodeling Within the Heart – Our

Salvation? ................................................................................................. 103

Michal Miko and Ivan Varga

8 The Non-cardiomyocyte Cells of the Heart. Their Possible

Roles in Exercise-Induced Cardiac Regeneration and 

Remodeling .............................................................................................. 117

Ivan Varga, Jan Kyselovič, Paulina Galfiova, and Lubos Danisovic

Part IV Exercise Benefits the Heart: Basic Science Evidence

9 Myocardial Infarction and Exercise Training: Evidence

from Basic Science .................................................................................. 139

Ivana C. Moraes-Silva, Bruno Rodrigues, Hélio J. Coelho-Junior,

Daniele Jardim Feriani, and Maria-Claudia Irigoyen

10 Cardiac Ischemia/Reperfusion Injury:

The Beneficial Effects of Exercise .......................................................... 155

Juliana Pereira Borges and Karine da Silva Verdoorn

11 Experimental Evidences Supporting the Benefits of Exercise

Training in Heart Failure ....................................................................... 181

Marcelo H.A. Ichige, Marcelo G. Pereira, Patrícia C. Brum,

and Lisete C. Michelini

12 Exercise Amaliorates Metabolic Disturbances and Oxidative

Stress in Diabetic Cardiomyopathy: Possible Underlying

Mechanisms ............................................................................................. 207

Ayman M. Mahmoud

13 Cardiac Aging – Benefits of Exercise, Nrf2 Activation and 

Antioxidant Signaling ............................................................................. 231

Madhusudhanan Narasimhan and Namakkal-Soorappan Rajasekaran

14 Cardiac Fibrosis: The Beneficial Effects of Exercise in 

Cardiac Fibrosis ...................................................................................... 257

Jan Kyselovič and John J. Leddy

15 Physical Exercise Is a Potential “Medicine” for Atherosclerosis ........ 269

Jian Yang, Richard Y. Cao, Rongrong Gao, Qiongyao Mi,

Qiying Dai, and Fu Zhu

16 Experimental Evidences Supporting Training-Induced Benefits

in Spontaneously Hypertensive Rats ..................................................... 287

Gustavo S. Masson and Lisete C. Michelini

17 Exercise Training in Pulmonary Hypertension and Right

Heart Failure: Insights from Pre- clinical Studies ................................ 307

Daniel Moreira-Gonçalves, Rita Ferreira-Nogueira, Mário Santos,

Ana Filipa Silva, Rita Ferreira, Adelino Leite-Moreira,

José Alberto Duarte, and Tiago Henriques-Coelho

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