Burgess STG, Shen C, Ferguson LA, O’Neill GT, Docherty K, Hunter N, Goldmann W
(2009) Identification of adjacent binding sites for the YY1 and E4BP4 transcription factors in
the ovine PrP (prion) gene promoter. J Biol Chem 284:6716–6724
Bellingham SA, Coleman LA, Masters CL, Camakaris J, Hill AF (2009) Regulation of prion
gene expression by transcription factors SP1 and metal transcription factor-1. J Biol Chem
284:1291–1301
Denman R, Potempska A, Wolfe G, Ramakrishna N, Miller DL (1991) Distribution and activ-
ity of alternatively spliced Alzheimer amyloid peptide precursor and scrapie Prp messenger-
Rnas on rat-brain polysomes. Arch Biochem Biophys 288:29–38
Rane NS, Chakrabarti O, Feigenbaum L, Hegde RS (2010) Signal sequence insufficiency
contributes to neurodegeneration caused by transmembrane prion protein. J Cell Biol
188:515–526
Chen R, Knez JJ, Merrick WC, Medof ME (2001) Comparative efficiencies of C-terminal
signals of native glycophosphatidylinositol (GPI)-anchored proproteins in conferring GPI-
anchoring. J Cell Biochem 84:68–83
Zhang H, Stockel J, Mehlhorn I, Groth D, Baldwin MA, Prusiner SB, James TL, Cohen
FE (1997) Physical studies of conformational plasticity in a recombinant prion protein.
Biochemistry 36:3543–3553
Decker L, ffrench-Constant C. (2004) Lipid rafts and integrin activation regulate oligoden-
drocyte survival. J Neurosci 24:3816–3825
Sun X, Fu Y, Gu M, Zhang L, Li D, Li H, Chien S, Shyy JY, Zhu Y (2016) Activation of
integrin alpha5 mediated by flow requires its translocation to membrane lipid rafts in vascular
endothelial cells. Proc Natl Acad Sci U S A 113:769–774
Mouillet-Richard S, Ermonval M, Chebassier C, Laplanche JL, Lehmann S, Launay JM,
Kellermann O (2000) Signal transduction through prion protein. Science 289:1925–1928
Roffe M, Beraldo FH, Bester R, Nunziante M, Bach C, Mancini G, Gilch S, Vorberg I, Castilho
BA, Martins VR, Hajj GN (2010) Prion protein interaction with stress-inducible protein 1
enhances neuronal protein synthesis via mTOR. Proc Natl Acad Sci U S A 107:13147–13152
Roucou X, Giannopoulos PN, Zhang Y, Jodoin J, Goodyer CG, LeBlanc A (2005) Cellular
prion protein inhibits proapoptotic Bax conformational change in human neurons and in
breast carcinoma MCF-7 cells. Cell Death Differ 12:783–795
Liang J, Pan Y, Zhang D, Guo C, Shi Y, Wang J, Chen Y, Wang X, Liu J, Guo X, Chen Z, Qiao
T, Fan D (2007) Cellular prion protein promotes proliferation and G1/S transition of human
gastric cancer cells SGC7901 and AGS. FASEB J 21:2247–2256
Meslin F, Hamai A, Gao P, Jalil A, Cahuzac N, Chouaib S, Mehrpour M (2007) Silencing of
prion protein sensitizes breast adriamycin-resistant carcinoma cells to TRAIL-mediated cell
death. Cancer Res 67:10910–10919
Du J, Pan Y, Shi Y, Guo C, Jin X, Sun L, Liu N, Qiao T, Fan D (2005) Overexpression and
significance of prion protein in gastric cancer and multidrug-resistant gastric carcinoma cell
line SGC7901/ADR. Int J Cancer 113:213–220
Malaga-Trillo E, Solis GP, Schrock Y, Geiss C, Luncz L, Thomanetz V, Stuermer CAO (2009)
Regulation of embryonic cell adhesion by the prion protein. PLoS Biol 7:576–590
Huc-Brandt S, Hieu N, Imberdis T, Cubedo N, Silhol M, Leighton PLA, Domaschke T,
Allison WT, Perrier V, Rossel M. 2014. Zebrafish prion protein PrP2 controls collective
migration process during lateral line sensory system development. PLoS One 9
Horton ER, Byron A, Askari JA, Ng DHJ, Millon-Fremillon A, Robertson J, Koper EJ, Paul
NR, Warwood S, Knight D, Humphries JD, Humphries MJ (2015) Definition of a consensus
integrin adhesome and its dynamics during adhesion complex assembly and disassembly. Nat
Cell Biol 17:1577–1587
Watts JC, Huo H, Bai Y, Ehsani S, Jeon AH, Shi T, Daude N, Lau A, Young R, Xu L, Carlson
GA, Williams D, Westaway D, Schmitt-Ulms G (2009) Interactome analyses identify ties of
PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-
derived chaperones. PLoS Pathog 5:e1000608
