Infectious Agents Associated Cancers Epidemiology and Molecular Biology

(Nora) #1

222



  1. Kuwahara C, Takeuchi AM, Nishimura T, Haraguchi K, Kubosaki A, Matsumoto Y, Saeki K,
    Matsumoto Y, Yokoyama T, Itohara S, Onodera T (1999) Prions prevent neuronal cell-line
    death. Nature 400:225–226

  2. Brown DR, Wong BS, Hafiz F, Clive C, Haswell SJ, Jones IM (1999) Normal prion protein
    has an activity like that of superoxide dismutase. Biochem J 344:1–5

  3. Brown DR, Besinger A (1998) Prion protein expression and superoxide dismutase activity.
    Biochem J 334:423–429

  4. Brown DR, Clive C, Haswell SJ (2001) Antioxidant activity related to copper binding of
    native prion protein. J Neurochem 76:69–76

  5. Haigh CL, McGlade AR, Collins SJ (2015) MEK1 transduces the prion protein N2 fragment
    antioxidant effects. Cell Mol Life Sci 72:1613–1629

  6. Wong BS, Pan T, Liu T, Li RL, Gambetti P, Sy MS (2000) Differential contribution of super-
    oxide dismutase activity by prion protein in vivo. Biochem Bioph Res Co 273:136–139

  7. Rachidi W, Vilette D, Guiraud P, Arlotto M, Riondel J, Laude H, Lehmann S, Favier A (2003)
    Expression of prion protein increases cellular copper binding and antioxidant enzyme activi-
    ties but not copper delivery. J Biol Chem 278:9064–9072

  8. Wong BS, Liu T, Li R, Pan T, Petersen RB, Smith MA, Gambetti P, Perry G, Manson JC,
    Brown DR, Sy MS (2001) Increased levels of oxidative stress markers detected in the brains
    of mice devoid of prion protein. J Neurochem 76:565–572

  9. Klamt F, Dal-Pizzol F, Conte da Frota ML, Walz R Jr, Andrades ME, da Silva EG, Brentani
    RR, Izquierdo I, Fonseca Moreira JC (2001) Imbalance of antioxidant defense in mice lack-
    ing cellular prion protein. Free Radic Biol Med 30:1137–1144

  10. Williams WM, Stadtman ER, Moskovitz J  (2004) Ageing and exposure to oxidative stress
    in vivo differentially affect cellular levels of PrP in mouse cerebral microvessels and brain
    parenchyma. Neuropathol Appl Neurobiol 30:161–168

  11. McLennan NF, Brennan PM, McNeill A, Davies I, Fotheringham A, Rennison KA, Ritchie
    D, Brannan F, Head MW, Ironside JW, Williams A, Bell JE (2004) Prion protein accumula-
    tion and neuroprotection in hypoxic brain damage. Am J Pathol 165:227–235

  12. Weise J, Doeppner TR, Muller T, Wrede A, Schulz-Schaeffer W, Zerr I, Witte OW, Bahr
    M (2008) Overexpression of cellular prion protein alters postischemic Erk1/2 phosphoryla-
    tion but not Akt phosphorylation and protects against focal cerebral ischemia. Restor Neurol
    Neurosci 26:57–64

  13. Spudich A, Frigg R, Kilic E, Kilic U, Oesch B, Raeber A, Bassetti CL, Hermann DM (2005)
    Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and
    STAT-1. Neurobiol Dis 20:442–449

  14. Beraldo FH, Soares IN, Goncalves DF, Fan J, Thomas AA, Santos TG, Mohammad AH,
    Roffe M, Calder MD, Nikolova S, Hajj GN, Guimaraes AL, Massensini AR, Welch I, Betts
    DH, Gros R, Drangova M, Watson AJ, Bartha R, Prado VF, Martins VR, Prado MA (2013)
    Stress-inducible phosphoprotein 1 has unique cochaperone activity during development and
    regulates cellular response to ischemia via the prion protein. FASEB J 27:3594–3607

  15. Mitteregger G, Vosko M, Krebs B, Xiang W, Kohlmannsperger V, Nolting S, Hamann GF,
    Kretzschmar HA (2007) The role of the octarepeat region in neuroprotective function of the
    cellular prion protein. Brain Pathol 17:174–183

  16. Doeppner TR, Kaltwasser B, Schlechter J, Jaschke J, Kilic E, Bahr M, Hermann DM, Weise
    J  (2015) Cellular prion protein promotes post-ischemic neuronal survival, angioneurogen-
    esis and enhances neural progenitor cell homing via proteasome inhibition. Cell Death Dis
    6:e2024

  17. Shyu WC, Lin SZ, Chiang MF, Ding DC, Li KW, Chen SF, Yang HI, Li H (2005)
    Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a
    stroke rat model. J Neurosci 25:8967–8977

  18. Guitart K, Loers G, Buck F, Bork U, Schachner M, Kleene R (2016) Improvement of neu-
    ronal cell survival by astrocyte-derived exosomes under hypoxic and ischemic conditions
    depends on prion protein. Glia 64:896–910


X. Yang et al.
Free download pdf