Nucleic Acids in Chemistry and Biology

Wyman’s concept
median ligand activity 352
wyosine
fluorescence 430
minor tRNA base 87

xanthine oxidase
allopurinol therapy for gout
123–124
Xeroderma pigmentosum
nucleotide excision 327

repair deficiency 330, 332, 333

X-ray crystallography 438–439

molecular replacement 438

multiple isomorphous replacement,

MIR

5-bromodeoxyuridine 438

single-wavelength anomalous

dispersion, SAD 438

Yoshikawa reaction

nucleotide synthesis 111

Zachau, H.

tRNA structure 8

zalcitabine, ddC

anti-viral nucleoside

analogue 130, 131

Z-DNA

left-handed DNA

structure 25, 30–32

zidovudine, AZT

AIDS therapy nucleoside

analogue 130

470 Subject Index

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