Table 12.1Personal and environmental allergy casesLocation# patients in studyRoute of exposureClinical presentationAllergens (molecularweights)ReferenceMadrid,Spain1Smoking and contactPapular lesions,itching, generalizederythema and palpebralangioedema10, 26, 38, 69(Perez-Bustamanteet al.2007)St. Louis,MO (USA)1SmokingAnaphylaxis, nasal andpharyngeal pruritus,lacrimation, nasalcongestion, dyspneaand wheezingN/A(Liskow et al. 1971)Basel,Switzerland1SmokingItching,rhinoconjunctivitisN/A(Stockli andBircher2007)Toronto,Canada7Smoking and contactRhinitis, conjunctivitis,periorbital angioedemaand dermatitis. Onepatient withanaphylaxis resultingin GI cramping andvomiting.N/A(Basharat et al. 2011)Bilbao,Madrid andPamplona,Spain1Smoking and contactUrticaria, rhinorrhea,palpebral edema,itching9, 14, 35 and 100(Gamboa et al. 2007)Madrid,Spain1Smoking and contactItching, rhinorrhea,pharyngeal pruritusN/A(Anibarro andFontella1996)Miami, FL(USA)1Smoking moldcontaminated marijuanaFever, wheezingN/A(Llamas et al. 1978)(continued)266 A.P. Nayak et al.