Cannabis sativa L. - Botany and Biotechnology

Table 12.1

(continued)

Location

# patients in study

Route of exposure

Clinical presentation

Allergens (molecularweights)

Reference

Munich,GermanyandValladolid,Spain

16 (8 Spanish and 8German)

All 8 Spanish patientswere identi

fied as

drug-dependent users ofCannabis

.Cannabis

use

was reported unknownamong German patients

Asthma, conjunctivitis,rhinitis and urticariawere commonmanifestations. In arare case anaphylaxiswas also noted.

IgE reactivityspeci

fically tested to Pru

p 3 (LTP)

(Rihs et al.

2014

)

Antwerp,Belgium

21 patients reporting oralallergy syndrome(OAS) or food-relatedallergies, including 12patients with respiratoryand cutaneous reactions toC. sativa

All 12 patients wereidenti

fied to have

exposure to marijuana orhashish by smoking orcutaneous transmission

Rhinitis, conjunctivitis,asthma and contacturticaria and itching

N/A

(Ebo et al.

2013

)

Fukuoka,Japan

1

Uncharacterizedexposure

Uncharacterizedclinical observations

10, 14, 45, 60 and 68

(Tanaka et al. 1998

)

Izmir,Turkey

1

Smoking exposure

Erythematous,vesiculobullous, scalyrash

N/A

(Ozyurt et al.

2014

)

Tucson, AZ(USA)

63

Environmental exposureto

C. sativa

pollen

Allergic rhinitis,asthma, urticaria andatopic dermatitis

N/A

(Freeman

1983

)

Papillion,NE (USA)

127 total with 78 patientswith SPT determinedtowards

C. sativa

extract

Environmental exposureto

C. sativa

pollen

Rhinitis andasthma/asthma-likesymptoms

N/A

(Stokes et al.

2000

)

Lucknow,India

48 total with 7 patientswith SPT determinedtowards

C. sativa

pollen

Possibly environmentalexposure to

C. sativa

pollen

Nasobronchial allergy

N/A

(Prasad et al.

2009

)

268 A.P. Nayak et al.