- Weinberg RA (1995) The retinoblastoma
protein and cell cycle control. Cell
81:323–330 - Paget S (1989) The distribution of secondary
growths in cancer of the breast. 1889. Cancer
Metastasis Rev 8(2):98–101 - Fidler IJ, Poste G (2008) The “seed and soil”
hypothesis revisited. Lancet Oncol 9(8):808 - Wang X et al (2011) Residual embryonic cells
as precursors of a Barrett’s-like metaplasia.
Cell 145(7):1023–1035 - Koshland DE, Goldbeter A, Stock JB (1982)
Amplification and adaptation in regulatory
and sensory systems. Science (New York,
NY) 217(4556):220–225 - Ao P (2009) Global view of bionetwork
dynamics: adaptive landscape. J Genet Geno-
mics 36(2):63–73 - Zhu XM et al (2004) Robustness, stability and
efficiency of phage lambda genetic switch:
dynamical structure analysis. J Bioinform
Comput Biol 2(4):785–817 - Li F et al (2004) The yeast cell-cycle network
is robustly designed. Proc Natl Acad Sci USA
101(14):4781–4786 - Zhu X et al (2007) Efficiency, robustness, and
stochasticity of gene regulatory networks in
systems biology:λswitch as a working exam-
ple. In: Choi S (ed) Introduction to systems
biology. Humana, New York, pp 336–371 - Bizzarri M et al (2011) Fractal analysis in a
systems biology approach to cancer. Semin
Cancer Biol 21(3):175–182 - Pastan I, Gottesman M (1987) Multiple-drug
resistance in human cancer. N Engl J Med 316
(22):1388–1393 - Gimbrone MA et al (1972) Tumor dormancy
in vivo by prevention of neovascularization. J
Exp Med 136(2):261–276 - Hartwell LH et al (1999) From molecular to
modular cell biology. Nature 402(6761
Suppl):C47–C52 - Akhurst RJ, Derynck R (2001) TGF-βsignal-
ing in cancer—a double-edged sword. Trends
Cell Biol 11(Supplement 1):S44–S51 - Feng G-S (2012) Conflicting roles of mole-
cules in hepatocarcinogenesis: paradigm or
paradox. Cancer Cell 21(2):150–154 - Kauffman S (2008) Control circuits for deter-
mination and transdetermination: interpret-
ing positional information in a binary
epigenetic code. In: Ciba foundation sympo-
sium 29 - cell patterning. Wiley, Chichester,
pp 201–221 - Auffray C, Chen Z, Hood L (2009) Systems
medicine: the future of medical genomics and
healthcare. Genome Med 1(1):2 - Hood L, Flores M (2012) A personal view on
systems medicine and the emergence of pro-
active P4 medicine: predictive, preventive,
personalized and participatory. N Biotechnol
29(6):613–624 - Chalancon G et al (2012) Interplay between
gene expression noise and regulatory network
architecture. Trends Genet 28(5):221–232 - Vital-Lopez FG, Memisˇevic ́ V, Dutta B
(2012) Tutorial on biological networks.
Wiley Interdiscip Rev Data Min Knowl Discov
2(4):298–325 - Ao P et al (2008) Cancer as robust intrinsic
state of endogenous molecular-cellular net-
work shaped by evolution. Med Hypotheses
70(3):678–684 - Wang G et al (2013) From Phage lambda to
human cancer: endogenous molecular-
cellular network hypothesis. Quant Biol 1
(1):32–49 - Yuan R et al (2017) Cancer as robust intrinsic
state shaped by evolution: a key issues review.
Rep Prog Phys 80(4):042701 - Garber K (2001) Beyond the Nobel prize: cell
cycle research offers new view of cancer. J Natl
Cancer Inst 93(23):1766–1768 - Nurse P (2000) A long twentieth century of
the cell cycle and beyond. Cell 100(1):71–78 - Takahashi K et al (2007) Induction of plurip-
otent stem cells from adult human fibroblasts
by defined factors. Cell 131(5):861–872 - Huang P et al (2011) Induction of functional
hepatocyte-like cells from mouse fibroblasts by
defined factors. Nature 475(7356):386–389 - Ferrell JE Jr, Tsai TY-C, Yang Q (2011) Mod-
eling the cell cycle: why do certain circuits
oscillate? Cell 144(6):874–885 - Spencer SL, Sorger PK (2011) Measuring and
modeling apoptosis in single cells. Cell 144
(6):926–939 - Meyer BJ, Maurer R, Ptashne M (1980) Gene
regulation at the right operator (OR) of bac-
teriophageλ: II. OR1, OR2, and OR3: their
roles in mediating the effects of repressor and
cro. J Mol Biol 139(2):163–194 - Yuh C-H, Bolouri H, Davidson EH (1998)
Genomic cis-regulatory logic: experimental
and computational analysis of a sea urchin
gene. Science 279(5358):1896–1902 - Baker SG, Kramer BS (2011) Systems biology
and cancer: promises and perils. Prog Biophys
Mol Biol 106(2):410–413
242 Gaowei Wang et al.